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ea0056gp199 | Pituitary Basic | ECE2018

Prominent expression of MAX and MEG3, despite lack of mutations in MAX, suggest a potential role for 14q genes in pituitary adenomas

Ibanez-Costa Alejandro , Leton Rocio , Rivero-Cortes Esther , Alvarez-Escola Cristina , Poyo-Guerrero Paloma Rodriguez , Gavilan-Villarejo Inmaculada , Korbonits Marta , Marazuela Monica , Galvez-Moreno Maria Angeles , Soto-Moreno Alfonso , Robledo Mercedes , Castano Justo P , Luque Raul M

Pituitary adenomas (PA), as well as pheochromocytomas and paragangliomas, are neuroendocrine tumors that arise from cells derived from the pituitary, adrenal and extra-adrenal nervous system, respectively. Recent studies have identified a growing series of susceptibility genes for these pathologies. Some genes may be associated with the development of both types of pathologies, as it is the case for succinate dehydrogenase complex genes, while, PAs have not been reported to da...

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Prominent expression of MAX and MEG3, despite lack of mutations in MAX, suggest a potential role for 14q genes in pituitary adenomas

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